Groupe de Recherche

Martin Beaulieu

Research Areas
Animal models, Behavioral study (mice), Biochemistry, Surgery (mice), Molecular Biology, Cell Culture, Neuropharmacology, Microscopy (Opt&Elec), Transgenic/knockout, siRNA.

Denis Boudreau

Daniel Côté

Research Areas
Video rate microscopy for multimodal live animal imaging, Coherent Raman development for live imaging, Microendoscopic imaging of brain structures, Fast optical measurements of neuronal activity.

Paul De Koninck

Research Description
Our lab investigates the cellular and molecular mechanisms used by neurons to decode synaptic and electrical activities that propagate through neural circuits. We are particularly interested in learning how these mechanisms contribute to synaptic remodeling and to the maintenance and modifications of brain circuit connectivity. Synaptic remodelling in the brain during development and in adult life is thought to represent fundamental cellular processes of learning and memory.

Yves De Koninck

Research Areas
Spinal cord, sensory physiology, synaptic transmission, pain, electrophysiology, patch clamp, biophysics, cellular maging, fluorescence spectroscopy, nanoprobes.

Martin Deschênes

André Parent

Research Areas
Basal Ganglia, Postnatal Neurogenesis, Neurodegenerative Disord., Animal Models, Neuroanatomy, Immunocytochemistry, Human Brain Banking, Comparative Neurology, Single-Cell Labeling

Martin Parent

Research Areas
Basal ganglia, electron microscopy, Parkinson’s disease, Huntington’s disease, neuromorphology, primates.

Michel Piché

Armen Saghatelyan

Research objectives of our group are:
To elucidate the cellular and molecular mechanisms governing adult neurogenesis. To employ these mechanisms for cell replacement therapies in animal models of neurodegenerative diseases and stroke. To understand the functional role of adult OB neurogenesis.

Lisa Topolnik

Research Interests
We use a combination of patch-clamp whole-cell electrophysiology and two-photon microscopy in mouse acute hippocampal slices to study: The physiological properties of ISIs, input-specific synaptic integration, the properties of inhibitory synapses made by ISIs onto their GABAergic targets, the role of ISIs in the regulation of O-LM interneuron function and network operation.

Réal Vallée

 

Publications Récentes

Pagès S, et al.
Front Cell Neurosci. 2011

Optophysiological approach to resolve neuronal action potentials with high spatial and temporal resolution in cultured neurons.
Read more...

LeChasseur Y et al.
Nat Methods. 2011

A microprobe for parallel optical and electrical recordings from single neurons in vivo.
Read more...

Swift et al. PNAS 2011
Quantification of receptor tyrosine kinase transactivation through direct dimerization and surface density measurements in single cells.
Read more...

AddThis Social Bookmark Button